I tried 352 for one game this past WL. The delays I experienced were horrendous. My opponent had a better connection, which meant faster players, quicker reactions, etc. All he did was counter, speed burst, and run around my slow grandpa with amnesia defense. I lost that game 5-2. It was the most goals I allowed this past weekend.
My cb's were shadow Nesta in the middle, "i pulled him from a pack" Shadow Pique LCB, and Shadow Lenglet, RCB...
Maybe with a better connection, and faster response ratios, 3 in the back would work better for me.